Protective Effect of Alpha Lipoic Acid against Phenytoin Induced Behavioral Abnormalities in Rats
نویسندگان
چکیده
منابع مشابه
Protective Effect of Alpha Lipoic Acid against Phenytoin Induced Behavioral Abnormalities in Rats
Background: Long term administration of antiepileptic drug phenytoin is reported to cause behavioral abnormalities mediated via oxidative stress. The effect of an antioxidant alpha lipoic acid (ALA) against phenytoin induced behavioral abnormalities was investigated. Methods: The study was carried out in albino wistar rats. The rats were divided into five groups of six animals each. Group 1 rec...
متن کاملHep atop rotective Effect of Alpha Lipoic Acid Against Bromobenzene-Induced Liver Damage in Rats
The hepatic lesion produced as a result of oxidative stress is of wide occurrence. In this study, the effect of the antioxidant alpha lipoic acid (ALA) on liver necrosis induced by bromobenzene (BB), which is known to produce oxidative stress, in rats had been studied. Treatment of animals with ALA for one week before the induction of chemical liver injury with BB had been carried out. Various ...
متن کاملthe effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولProtective effects of alpha-lipoic Acid on oleic Acid-induced acute lung injury in rats.
BACKGROUND Oxidative stress is believed to be an important factor in the pathogenesis of acute lung injury (ALI). AIMS The aim of this study was to investigate the possible protective role of alpha-lipoic acid (α-LA) on oleic acid (OA)-induced ALI in rats. STUDY DESIGN Animal experiment. METHODS A total of thirty-five rats were divided into five groups in the study. Group 1 served as a co...
متن کاملProtective Efficacy of Alpha-lipoic Acid against AflatoxinB1-induced Oxidative Damage in the Liver
Alpha-lipoic acid (α-LA) is not only involved in energy metabolism, but is also a powerful antioxidant that can protect against hepatic oxidative stress induced by some drugs, toxins, or under various physiological and pathophysiological conditions. Here, we investigated the effect of α-LA against liver oxidative damage in broilers exposed to aflatoxin B1 (AFB1). Birds were randomly divided int...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Molecular Biomarkers & Diagnosis
سال: 2015
ISSN: 2155-9929
DOI: 10.4172/2155-9929.1000241